Candida albicans-Cell Interactions Activate Innate Immune Defense in Human Palate Epithelial Primary Cells via Nitric Oxide (NO) and β-Defensin 2 (hBD-2)

AR Casaroto, RA da Silva, S Salmeron, MLR Rezende… - Cells, 2019 - mdpi.com
… we performed experiments with the immortalized human gingival epithelial cell line OBA-9 in
… Other studies of human oral diseases have been performed with normal oral epithelial cells

Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans

M Zhao, M Zhang, K Xu, K Wu, R Xie, R Li… - Frontiers in …, 2022 - frontiersin.org
… Both immune cells and nonimmune cells can produce EVs, which … growth or promote
disease development (7–10). EVs derived from oral mucosal epithelial cells can inhibit the growth

… Eugenia uniflora extract on adhesion to human buccal epithelial cells, biofilm formation, and cell surface hydrophobicity of Candida spp. from the oral cavity of kidney …

LBFC Souza, WP Silva-Rocha, MRA Ferreira… - Molecules, 2018 - mdpi.com
… However, two highly biofilm-producing strains of Candida tropicalis had a very large … growth
inhibition, E. uniflora may interfere with the expression of some virulence factors of Candida

In vitro inhibitory activity of probiotic products against oral Candida species

C Zhao, X Lv, J Fu, C He, H Hua… - Journal of Applied …, 2016 - academic.oup.com
human oral mucosa tissue. Bacillus subtilis exhibited clear zones of inhibition for Candida
albicans and Candida … The epithelial cells were cultured in Dulbecco's modified Eagle's (…

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin

AH Verma, JP Richardson, C Zhou, BM Coleman… - Science …, 2017 - science.org
… This prompted us to assess the role of candidalysin, a hyphal-associated peptide that
damages oral epithelial cells and triggers production of inflammatory cytokines including IL-1. …

Different Host Immunological Response to C. albicans by Human Oral and Vaginal Epithelial Cells

Y Gao, G Liang, Q Wang, X She, D Shi, Y Shen, X Su… - Mycopathologia, 2019 - Springer
… Anti-Candida activity of epithelial cells has been recognized lately since epithelial cells can
inhibit the growth … By CFU recovery, we find that oral cells can hardly inhibit the formation of …

Oropharyngeal candidiasis: fungal invasion and epithelial cell responses

M Swidergall, SG Filler - PLoS pathogens, 2017 - journals.plos.org
… defensins and cathelicidins, that either kill or inhibit the growth of C. albicans. Different HDPs
… unable to invade reconstituted human oral epithelium in vitro and causes minimal epithelial

Determination of the effects of cinnamon bark fractions on Candida albicans and oral epithelial cells

MP Veilleux, D Grenier - BMC complementary and alternative medicine, 2019 - Springer
… The human oral epithelial cell line B11, which was kindly provided by S. Groeger (Justus
Liebig … In this study, we showed a dose-dependent inhibitory effect of Cinnulin PF® on TNF-α-…

Candida and Porphyromonas gingivalis: the effect on wound closure in vitro

TM Haverman, AMGA Laheij, JJ de Soet… - Journal of oral …, 2017 - Taylor & Francis
… The inhibition of oral epithelial cell migration challenged with either C. glabrata or C… inhibition
of epithelial cell migration in this study. However, during all experiments, the epithelial cells

IL-1α released from oral epithelial cells upon candidalysin exposure initiates an early innate epithelial response

M Hanaoka, E Domae - International Immunology, 2021 - academic.oup.com
… We found that human oral epithelial cells released IL-1α rapidly … Oral candidiasis is an
opportunistic infection of the oral cavity of … Simultaneous inhibition of IL-1α and EGFR abrogates …